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A part of my messages cannot be sent. OCCASIONAL SMTP error. (McAfee?)

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I am having problems sending email to some external servers. I get the error message that the SMTP server timed out. Most mail sends OK though, and yesterday I was able to exchange a couple of emails with a person before Thunderbird decided to stop sending my mail to them. I can solve this by going on our webmail and sending the message there, so this seems to be a Thunderbird problem.

I am at the University of Iceland so they are my provider (reiknistofnun.hi.is) and my ISP. I am using Windows 7 Enterprise. My Windows 7 firewall is on. I have a McAFee virus protection installed, but I don't think it is enabled (see attached). I am using Thunderbird 45.3.0, but I have encountered the same problem with previous versions.

Thanks for your help!

I am having problems sending email to some external servers. I get the error message that the SMTP server timed out. Most mail sends OK though, and yesterday I was able to exchange a couple of emails with a person before Thunderbird decided to stop sending my mail to them. I can solve this by going on our webmail and sending the message there, so this seems to be a Thunderbird problem. I am at the University of Iceland so they are my provider (reiknistofnun.hi.is) and my ISP. I am using Windows 7 Enterprise. My Windows 7 firewall is on. I have a McAFee virus protection installed, but I don't think it is enabled (see attached). I am using Thunderbird 45.3.0, but I have encountered the same problem with previous versions. Thanks for your help!
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由Wayne Mery于修改

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Try with Windows in Safe Mode with Networking. That should disable McAfee altogether. AV scanning your outgoing would be my first suspicion.