Thunderbird falls very often in not responing state for about 2 min.
The program falls into Not responing state for about 1-2 min., usually when I write emails. the recipy to start Windows in Safe mode with networking and Thunderbird in Safe mode does not work, because my laptop does not have cable Ethernet connection and WiFi is not supported in Safe mode. Starting in Safe mode withou network does not solve the problem.
Izabrano rješenje
Even with Defender, the suggestions above are still relevant. Which ones did you follow?
To really exclude anti-virus from the possible causes of your problems, you'd need to test with Windows safe mode.
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What is your anti-virus software?
It was Avast; trying to solve the problem I have changed to AVG, no difference. Let me add that my Windows 10 Home is 64-bit version 1709, OS Build 16299.371.
Izmjenjeno
Anti-virus software is most likely the culprit. These are some general suggestions to address this problem:
Create an exception in your anti-virus software for the Thunderbird profile folder, so that the anti-virus real-time scanner will not scan it. http://kb.mozillazine.org/Profile_folder_-_Thunderbird
Don't let your anti-virus software scan incoming and outgoing messages.
Don't let your anti-virus software scan attachments.
Don't let your anti-virus software intercept your secure connection to the server.
Remove any add-ons your anti-virus software may have installed in Thunderbird.
Keep it working. http://kb.mozillazine.org/Keep_it_working_-_Thunderbird
And last but not least, backup your Thunderbird profile on a regular basis. https://support.mozilla.org/kb/profiles-where-thunderbird-stores-user-data#w_backing-up-a-profile
Beyond that, I'd dump any 3rd party anti-virus software and simply stick with Microsoft Security Essentials. https://www.microsoft.com/en-us/safety/pc-security/microsoft-security-essentials.aspx
Unfortunately, it happens that the anti-virus software is not the culprit. Nothing of your suggestions helps... Even runnig without third-party anti-virus program and rely on Windows 10 Defender only.
Odabrano rješenje
Even with Defender, the suggestions above are still relevant. Which ones did you follow?
To really exclude anti-virus from the possible causes of your problems, you'd need to test with Windows safe mode.
Izmjenjeno
At the end it came out it is the anti-virus programme. In Avast and AVG I tried to prevent scanning of the Thunderbird profile folder, but it didn't help. Then I uninstalled all third party anti-virus programmes and return the protection to Windows Defender with standard settings. This solved the problem. Thanks to crist1 a lot!