Workaround...

From http://www.pcworld.com/article/200103/fix_outlook_general_failure_error_for_email_links.html:

Hassle-Free PC Fix Outlook 'General Failure' Error for E-Mail Links

By Rick Broida, PCWorld Jun 29, 2010 12:45 PM

(Note: These instructions apply to Windows Vista and 7 only.)

1. Click Start, type regedit, and then press Enter.

2. Navigate to the following entry: HKEY_CLASSES_ROOT\FirefoxURL\shell\open\ddeexec

3. In the center pane, double-click the Default entry, then remove whatever value is there (it'll probably be a weird string of numbers and commas).

4. Click OK, then exit Regedit.

5. If Outlook and/or Firefox are open, close them, then restart them.

Thanks for the help, but for some reason that I don't understand, the problem has disappeared. i have now upgraded to 3.6.16, but I think the probem went away before this.

When I eliminated the values, and tried to open the link, it caused Firefox to crash instead of giving me the error message that it could not load the page. This problem seemed to occur when I upgraded Firefox 5.0. I am using Windows 7, Outlook 2010. Begrudgingly, I make IE Explorer the default, and the links now work fine. I will have to sit by while a solution is arrived at.

Every single time that I have to do an update on Firefox I then have to go back into the regedit and follow the directions again in order to prevent this error. The issue should be corrected by Mozilla on their next update. To be honest, it is kind of annoying!! This has been an issue for several months, and I am tired of having to fix their mistakes! MOZILLA!!! PLEASE FIX THIS ISSUE!!!

I HAVE ATTACHED A SCREEN SHOT OF THE ERROR THAT I AM GETTING.

I've solved the problem by changing to Chrome. I found that the latest release of Firefox kept crashing and I don't have the time to dig around to solve their problems. I may come back to FF when there is a new release.

Work around did not work for me as there was NO string of characters in HKEY_CLASSES_ROOT\FirefoxURL\shell\open\ddeexec